This is a link post for the Biosecurity Fundamentals Curriculum
Core:
Gain of Function and DURC
◦ Designer bugs: how the next pandemic might come from a lab (20 mins)
◦ Between Publishing and Perishing? H5N1 Research Unleashes Unprecedented Dual-Use Research Controversy (30 mins)
◦ Horsepox synthesis: A case of the unilateralist’s curse? (20 mins)
◦ Biodefense in the Age of Synthetic Biology (2018)
▪ Summary, p1-8 (20 mins)
Biosafety
◦ Biosafety Levels 1, 2, 3, & 4 - Lab Manager (2010) (5 mins)
◦ High-risk human-caused pathogen exposure events from 1975-2016
▪ Spend ~10 minutes looking through table 1
Optional:
Examples of assessing new technologies
◦ Assessing new technologies. Have a look at table 1 in this paper to get a sense of frameworks that can be applied to new technologies to assess risk
▪ Biosecurity risks associated with vaccine platform technologies
◦ Next Steps for Access to Safe, Secure DNA Synthesis
◦ Engineering Gene Safety,
◦ DARPA’s Biological Technologies Office runs extremely interesting biodefense research programs; this is a comprehensive summary of one of them.
Next in the Biosecurity Sequence
Advances in biotechnology and a note on Information Hazards
Advances in biotechnology and a note on Information Hazards